Pharmacology

Introduction/Overview Leprosy, also known as Hansen's disease, is a chronic granulomatous infection caused by the obligate intracellular bacillus Mycobacterium leprae. The pharmacology of antileprotic drugs constitutes a specialized domain within…

Introduction/Overview Tuberculosis remains a significant global health challenge, with an estimated 10 million new cases and 1.3 million deaths reported annually. The pharmacological management of tuberculosis is complex, requiring prolonged…

Introduction/Overview Tuberculosis (TB) remains a major global health challenge, ranking among the leading causes of death from a single infectious agent. The pharmacology of antitubercular drugs constitutes a cornerstone of…

Introduction/Overview The tetracyclines and chloramphenicol represent two distinct but historically significant classes of broad-spectrum, bacteriostatic antibiotics. Their discovery in the mid-20th century marked a pivotal advancement in antimicrobial chemotherapy, providing…

Introduction/Overview The quinolone and fluoroquinolone class of synthetic antimicrobial agents represents a cornerstone of modern antibacterial chemotherapy. Originating from the discovery of nalidixic acid in the 1960s, subsequent structural modifications…

1. Introduction/Overview The quinolone and fluoroquinolone class of antimicrobial agents represents a cornerstone of modern antibacterial chemotherapy. Originating from the discovery of nalidixic acid in the 1960s, subsequent structural modifications…

1. Introduction/Overview Sulfonamides represent one of the oldest classes of synthetic antibacterial agents, with their therapeutic introduction in the 1930s marking the dawn of the modern antimicrobial era. These agents,…