Pharmacology

Introduction/Overview Domperidone is a benzimidazole derivative that functions as a selective peripheral dopamine D2 and D3 receptor antagonist. It is primarily employed as an antiemetic and gastroprokinetic agent, facilitating the…

Introduction/Overview Sucralfate represents a distinctive therapeutic agent within the pharmacopeia for gastrointestinal disorders, functioning primarily through local, non-systemic mechanisms. As a complex salt of sucrose octasulfate and polyaluminum hydroxide, it…

Introduction/Overview Famotidine is a competitive antagonist of histamine at the H2 receptor, belonging to the class of medications known as H2 receptor antagonists (H2RAs). Since its introduction in the 1980s,…

Introduction/Overview Esomeprazole represents a cornerstone agent in the pharmacological management of acid-related disorders. As the S-isomer of omeprazole, it was developed to provide enhanced efficacy and consistency in gastric acid…

1. Introduction/Overview Pantoprazole is a benzimidazole derivative that functions as a potent inhibitor of gastric acid secretion. As a member of the proton pump inhibitor class, it represents a cornerstone…

1. Introduction/Overview Vitamin D, specifically in its physiologically active hormonal form, represents a critical secosteroid hormone with pleiotropic effects extending far beyond its classical role in calcium and phosphate homeostasis.…

Introduction/Overview Calcitonin is a polypeptide hormone primarily involved in calcium and bone metabolism. Originally discovered in 1961 by Copp and Cheney, it is secreted by the parafollicular cells (C-cells) of…

Introduction/Overview Calcitonin is a polypeptide hormone primarily involved in calcium and bone homeostasis. It is secreted by the parafollicular cells (C-cells) of the thyroid gland in mammals, though in non-mammalian…

Introduction/Overview Alendronate sodium is a nitrogen-containing bisphosphonate that represents a cornerstone in the pharmacological management of metabolic bone diseases, most notably osteoporosis. Its development and clinical introduction marked a significant…

Introduction/Overview Alendronate sodium is a nitrogen-containing bisphosphonate that represents a cornerstone in the pharmacological management of metabolic bone diseases, most notably osteoporosis. Its development and clinical adoption marked a significant…