Beta-Blockers ✓ Passing Score: 50% 📝 Questions: 12 🎓 Practice Quiz Welcome! This is a practice quiz to test your knowledge. Please enter your details below to participate. Your results will be emailed to you upon completion. Your Information Name * Email * Start Quiz → Question 1 of 12 1 Which beta-blocker possesses intrinsic sympathomimetic activity (ISA)? * Metoprolol Esmolol Carvedilol Timolol Pindolol 2 Which of the following conditions is an absolute contraindication for the use of non-selective beta-blockers? * Paroxysmal Supraventricular Tachycardia (PSVT) Uncompensated Heart Failure (Acute decompensation) Hyperthyroidism Mild essential hypertension Stable Angina Pectoris 3 A patient taking a beta-blocker reports experiencing cold extremities and slight erectile dysfunction. These side effects are most likely related to: * Increased parasympathetic tone. Interference with thyroid hormone synthesis. Direct central nervous system depression. Blockade of $\\beta_2$ receptors in skeletal muscle vasculature. Peripheral vasoconstriction mediated by unopposed $\\alpha_1$ stimulation (especially with non-selective agents). 4 The primary mechanism by which beta-blockers reduce blood pressure in chronic hypertension is: * Blockade of $\\alpha_1$ receptors in peripheral vasculature. Decreased renin release from the juxtaglomerular cells. Direct vasodilation via nitric oxide release. Inhibition of angiotensin-converting enzyme. Increased baroreceptor sensitivity. 5 Nebivolol exerts its unique vasodilatory effect primarily through the enhanced release of: * Bradykinin Adiponectin Endothelin-1 Prostacyclin Nitric Oxide (NO) 6 Esmolol is unique among commonly used beta-blockers because it is primarily metabolized by: * Hydrolysis in the gut wall Plasma esterases Hepatic cytochrome P450 enzymes (CYP2D6) Renal excretion Glucuronidation in the liver 7 Which beta-blocker is unique because it also possesses $\\alpha_1$ receptor blocking activity, contributing significantly to its vasodilatory effects? * Carvedilol Sotalol Acebutolol Nebivolol Bisoprolol 8 In the management of pheochromocytoma, beta-blockers should *always* be administered only after adequate: * Diuresis Alpha-blockade Calcium channel blockade ACE inhibition Thiazide diuretic administration 9 Which beta-blocker has significant membrane-stabilizing activity (local anesthetic effect) at high doses? * Bisoprolol Esmolol Propranolol Metoprolol Atenolol 10 Which of the following beta-blockers is considered cardioselective (preferentially blocks $\\beta_1$ receptors) at therapeutic doses? * Labetalol Sotalol Propranolol Nadolol Atenolol 11 Which of the following side effects is commonly associated with the abrupt cessation of long-term oral beta-blocker therapy? * Hypotension and bradycardia Sedation and weight gain Tachyphylaxis Rebound diarrhea Increased myocardial contractility and angina 12 A patient with asthma is prescribed a beta-blocker for hypertension. Which agent would pose the highest risk of exacerbating bronchospasm? * Atenolol Metoprolol Esmolol Bisoprolol Propranolol ← Previous Next → Submit Quiz ✓
