Introduction to SAR The field of medicinal chemistry is replete with examples of how subtle changes in the molecular structure of a compound can have profound effects on its biological…
1. Introduction and Scope Antimicrobial stewardship (AMS) is a coordinated set of interventions aimed at optimizing the use of antimicrobial agents—including antibiotics, antivirals, antifungals, and antiparasitics—to ensure optimal clinical outcomes, minimize…
In the realm of pharmacology, the last century has witnessed a significant evolution in scientific research. This evolution has been driven by meticulously designed studies and continuous technological advancements that…
Introduction Structure-Activity Relationship (SAR) are an important aspect of chemistry that has been applied in many fields, particularly in drug design. It is a scientific method used to understand the…
Introduction Organophosphorus (OP) compounds, a broad class of chemicals primarily used as pesticides (insecticides) and, less ethically, as chemical warfare agents (nerve gases), pose a significant challenge in both developed and developing nations (Katzung,…