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Posts by Pharmacology Mentor

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thiazide diuretics
Posted inCVS Pharmacology

Pharmacology of Thiazide Diuretics

Thiazide diuretics are cornerstone antihypertensive and mild‑to‑moderate diuretic agents that inhibit the thiazide‑sensitive Na‑Cl cotransporter in the distal convoluted tubule, lowering blood pressure and mobilizing edema with characteristic effects on…
Read More Pharmacology of Thiazide Diuretics
Posted by Pharmacology Mentor August 31, 2023
loop diuretics
Posted inCVS Pharmacology

Pharmacology of Loop Diuretics

Introduction Loop diuretics are a cornerstone of therapy in conditions where rapid and potent diuresis (urine output) is required. By inhibiting sodium and chloride reabsorption in the thick ascending limb…
Read More Pharmacology of Loop Diuretics
Posted by Pharmacology Mentor August 31, 2023
first-order vs zero-order kinetics
Posted inGeneral Pharmacology

First-Order vs. Zero-Order Kinetics: What You Need to Know

Zero-Order Kinetics Definition: In zero-order kinetics, the rate of drug elimination is constant and does not depend on the drug concentration. This is often seen with drugs that saturate the…
Read More First-Order vs. Zero-Order Kinetics: What You Need to Know
Posted by Pharmacology Mentor August 31, 2023
prolongation of drug action
Posted inGeneral Pharmacology

Prolongation of Drug Action: A Complete Overview

Extending the duration of a drug action can offer several advantages, such as enhanced patient compliance, reduced frequency of dosing, and minimized side effects. However, it's crucial to understand that…
Read More Prolongation of Drug Action: A Complete Overview
Posted by Pharmacology Mentor August 31, 2023
kinetics of elimination
Posted inGeneral Pharmacology

Kinetics of Elimination: A Complete Overview of Mechanisms and Implications

Understanding the kinetics of how a drug is removed from the body is foundational for creating and adjusting rational dosage plans tailored to individual patient needs. Three key pharmacokinetic parameters…
Read More Kinetics of Elimination: A Complete Overview of Mechanisms and Implications
Posted by Pharmacology Mentor August 30, 2023
Diuretics
Posted inCVS Pharmacology

Diuretics and Antidiuretics: A Quick Reference Guide

Introduction Welcome to this all-encompassing guide to Diuretics and Antidiuretics. Whether you're a healthcare professional, a student, or someone simply interested in pharmacology, this article is designed to help you…
Read More Diuretics and Antidiuretics: A Quick Reference Guide
Posted by Pharmacology Mentor August 26, 2023
CTZ role in nausea and vomiting
Posted inGI Pharmacology

The Vomiting Centre and the Chemoreceptor Trigger Zone (CTZ)

1 · Introduction Vomiting (emesis) is an evolutionarily conserved defence reflex that forcefully expels gastric—and at times intestinal—contents through the mouth. Although the motor act seems singular, it is orchestrated by…
Read More The Vomiting Centre and the Chemoreceptor Trigger Zone (CTZ)
Posted by Pharmacology Mentor August 15, 2023
antiemetic drugs to relieve nausea and vomiting
Posted inGI Pharmacology

Pharmacology of Antiemetic Drugs

Introduction Nausea and vomiting are defensive reflexes that protect the body from ingested toxins and noxious substances, but they can also emerge from various benign or pathological stimuli. From motion sickness and morning…
Read More Pharmacology of Antiemetic Drugs
Posted by Pharmacology Mentor August 15, 2023
alpha-blockers
Posted inANS Pharmacology

Pharmacology of Alpha-Blockers

Introduction Alpha-adrenergic receptor antagonists, commonly referred to as alpha-blockers, form a crucial element in the pharmacologic management of several cardiovascular and genitourinary conditions. By blocking alpha-1 and/or alpha-2 adrenergic receptors, these agents…
Read More Pharmacology of Alpha-Blockers
Posted by Pharmacology Mentor August 14, 2023
beta-blockers
Posted inANS Pharmacology

Pharmacology of Beta-Blockers

Introduction Beta blockers, also known as β-adrenergic receptor antagonists, are a foundational class of cardiovascular drugs used to treat hypertension, ischemic heart disease, heart failure, arrhythmias, and other conditions. By…
Read More Pharmacology of Beta-Blockers
Posted by Pharmacology Mentor August 14, 2023

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