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Posts by Pharmacology Mentor

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About Pharmacology Mentor
helicobacter_pylori
Posted inGI Pharmacology

Helicobacter pylori Infection and Treatment

Introduction Helicobacter pylori (H. pylori) is a spiral-shaped, gram-negative bacterium that colonizes the human stomach and duodenum. First identified in the early 1980s, this organism quickly garnered attention due to its…
Read More Helicobacter pylori Infection and Treatment
Posted by Pharmacology Mentor November 21, 2023
ZE syndrome
Posted inGI Pharmacology

Zollinger-Ellison Syndrome (ZES)

I. Definition, Historical Perspective & Epidemiology Zollingerโ€“Ellison Syndrome (ZES) is a rare disorder characterized by gastrin-secreting tumors (โ€œgastrinomasโ€) of the pancreas or duodenum. These tumors lead to excessive gastric acid secretion,…
Read More Zollinger-Ellison Syndrome (ZES)
Posted by Pharmacology Mentor November 21, 2023
pharmacovigilence
Posted inClinical Pharmacology Pharmacology

Pharmacovigilance

1ย ยท Introduction Pharmacovigilance (PV) is the โ€œscience and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine-related problemโ€ (WHO). In an era of…
Read More Pharmacovigilance
Posted by Pharmacology Mentor November 19, 2023
oxytocin-word-love-hormone-medical-concept-scaled
Posted inmiscellaneous Pharmacology

Pharmacology of Oxytocin

Oxytocin, a neuropeptide hormone produced by the hypothalamus and secreted by the posterior pituitary gland, has garnered significant attention in recent years due to its diverse physiological and psychological effects.…
Read More Pharmacology of Oxytocin
Posted by Pharmacology Mentor November 17, 2023
tocolytic agents
Posted inmiscellaneous Pharmacology

Pharmacology of Tocolytic Agents

I. Introduction Tocolytic agents are medications used to inhibit uterine contractions and suppress premature labor, thereby prolonging pregnancy long enough for vital fetal benefitsโ€”particularly the administration of antenatal corticosteroids and safe…
Read More Pharmacology of Tocolytic Agents
Posted by Pharmacology Mentor November 17, 2023
thyroid and antithyroid drugs
Posted inEndocrine Pharmacology

Pharmacology of thyroid and antithyroid drugs – an Overview

Physiology of Thyroid Hormones Thyroid gland secretes T4 (thyroxine) and T3 (triiodothyronine); T3 is more potent, T4 is a prohormone converted peripherally to T3. Regulation: Hypothalamic-pituitary-thyroid axis (TRH โ†’ TSH โ†’ thyroid…
Read More Pharmacology of thyroid and antithyroid drugs – an Overview
Posted by Pharmacology Mentor November 11, 2023
Diphenhydramine
Posted inmiscellaneous Pharmacology

Pharmacology of Diphenhydramine

Introduction Diphenhydramine is a prototypical first-generation antihistamine with a long history of clinical use for allergic reactions, insomnia, motion sickness, and a variety of off-label applications. Its popularity in both prescription…
Read More Pharmacology of Diphenhydramine
Posted by Pharmacology Mentor November 11, 2023
levocetrizine
Posted inmiscellaneous Pharmacology

Pharmacology of Levocetirizine

Introduction Levocetirizine is a second-generation antihistamine, serving as the pharmacologically active R-enantiomer of cetirizine. Commonly prescribed for chronic allergic rhinitis and chronic idiopathic urticaria, levocetirizine delivers high efficacy with a…
Read More Pharmacology of Levocetirizine
Posted by Pharmacology Mentor November 11, 2023
antihistamine
Posted inmiscellaneous Pharmacology

Pharmacology of Histamine and Antihistamines

Overview Histamine is a ubiquitous biogenic amine that influences vascular tone and permeability, sensory nerve activity (especially itch), airway smooth muscle, gastric acid secretion, and central nervous system arousal. Among…
Read More Pharmacology of Histamine and Antihistamines
Posted by Pharmacology Mentor November 11, 2023
anithistamines
Posted inmiscellaneous Pharmacology

Histamine and Antihistamines

Introduction Histamine stands as a fundamental mediator in allergic reactions, inflammatory processes, and various physiological functions such as gastric acid secretion and neurotransmission. Endogenously, it is produced and stored predominantly…
Read More Histamine and Antihistamines
Posted by Pharmacology Mentor November 10, 2023

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