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Steady-State Concentration: Principles, Calculations, and Clinical Application

Steady state is a cornerstone concept in clinical pharmacokinetics. It connects dose, dosing interval, and patient-specific clearance to the drug concentrations that drive therapeutic and adverse effects. Yet, “steady state”…

Pharmacology Mentor August 31, 2025

General Pharmacology

Drug receptor classes

There are four classes of drug receptors, G protein-coupled receptors, ligand-gated ion channels, enzyme-linked receptors (receptor tyrosine kinases and cytokine receptors), and intracellular nuclear receptors, each of which transmits its…

Pharmacology Mentor August 31, 2025

miscellaneous Pharmacology

Over-the-Counter (OTC) Drugs in India: A Comprehensive Overview

Main Takeaway: India lacks a unified regulatory framework for OTC drugs, creating a complex landscape where medications not listed as prescription-only are sold over-the-counter. With 62.3% of urban populations practicing…

Pharmacology Mentor August 29, 2025

miscellaneous Pharmacology

Over-the-Counter (OTC) Drugs: A Comprehensive Overview

Main Takeaway: Over-the-counter (OTC) drugs are non-prescription medications available directly to consumers for self-treatment of common ailments. With over 800 active ingredients comprising more than 100,000 products, OTC medications provide…

Pharmacology Mentor August 29, 2025

miscellaneous Pharmacology

The Concept of P-Drugs in Rational Prescribing

Main Takeaway: A P-drug is a prescriber’s personal choice of first-line medicine for a specific indication, selected through a systematic and evidence-based process. Developing and maintaining a personal formulary of…

Pharmacology Mentor August 28, 2025

Antimicrobial Pharmacology

Pharmacology of Antiviral Drugs

Introduction Antiviral pharmacology has advanced from the single-agent era of idoxuridine to a modern arsenal including polymerase terminators, protease blockers, monoclonal antibodies, and host-directed entry inhibitors. Because viruses are obligate intracellular…

Pharmacology Mentor May 1, 2025

Endocrine Pharmacology

Pharmacotherapy of Type 1 Diabetes Mellitus

Introduction Type 1 diabetes mellitus (T1DM) is a complex autoimmune disorder requiring comprehensive pharmacological management throughout the patient's lifetime. Since the discovery of insulin over a century ago, numerous advancements…

Pharmacology Mentor April 24, 2025

Antimicrobial Pharmacology

Broad spectrum antibiotics – Tetracyclines and Chloramphenicol

Introduction Broad-spectrum antibiotics stand at the forefront of infectious disease management, enabling healthcare professionals to effectively target a wide variety of bacterial pathogens without waiting for definitive culture results. Within…

Pharmacology Mentor March 28, 2025

miscellaneous

A review on drug resistant mycoplasma pneumonia

Introduction Mycoplasma pneumoniae is a unique bacterial pathogen that causes a spectrum of respiratory infections, ranging from mild tracheobronchitis to severe pneumonia [1]. Unlike many typical bacteria, it lacks a…

Pharmacology Mentor February 17, 2025

miscellaneous Pharmacology

Pharmacotherapy of erectile dysfunction

Introduction Erectile dysfunction (ED), defined as the consistent or recurrent inability to attain or maintain an erection sufficient for satisfactory sexual performance, affects millions of men worldwide. Though once considered…

Pharmacology Mentor January 28, 2025

Steady-State Concentration: Principles, Calculations, and Clinical Application

Drug receptor classes

Over-the-Counter (OTC) Drugs in India: A Comprehensive Overview

Over-the-Counter (OTC) Drugs: A Comprehensive Overview

The Concept of P-Drugs in Rational Prescribing

Pharmacology of Antiviral Drugs

Pharmacotherapy of Type 1 Diabetes Mellitus

Broad spectrum antibiotics – Tetracyclines and Chloramphenicol

A review on drug resistant mycoplasma pneumonia

Pharmacotherapy of erectile dysfunction

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