Antimalarial Drugs

Which antimalarial drug is contraindicated in pregnancy due to teratogenic risk? *

Which drug is commonly used as a second‑line treatment for chloroquine‑resistant P. falciparum malaria? *

What is the primary adverse effect of quinine when used for malaria treatment? *

Which antimalarial drug should be avoided in patients with a history of QT prolongation? *

In the treatment of uncomplicated P. falciparum malaria, the WHO recommends a 3‑day regimen of which drug combination? *

What is the principal reason for using combination therapies (e.g., ACTs) in malaria treatment? *

Which antimalarial drug is a prodrug that requires hepatic activation to produce its active metabolite? *

Which drug class is NOT typically used in antimalarial therapy? *

For prophylaxis against malaria in travelers to endemic areas, which drug regimen is recommended for short‑term exposure (≤4 weeks)? *

Which of the following antimalarial agents has the longest half‑life and is therefore used for post‑treatment prophylaxis? *

In a patient with G6PD deficiency, which antimalarial drug should be avoided due to risk of hemolysis? *

Which antimalarial drug is known to cause a purpuric rash in a subset of patients due to its effect on platelet function? *

What is the main reason for the emergence of artemisinin resistance in Southeast Asia? *

What is the recommended dose of artemisinin‑based combination therapy for a 70‑kg adult with uncomplicated falciparum malaria? *

Which antimalarial combination is most effective for severe malaria requiring intravenous therapy? *

In a patient with severe malaria who cannot tolerate oral medications, which antimalarial drug can be administered intravenously? *

Which antimalarial agent can be used to treat both uncomplicated malaria and provide prophylaxis for travelers? *

Which antimalarial drug is specifically used for radical cure of P. vivax and P. ovale infections by targeting hypnozoites? *

Which antimalarial drug is most commonly used as a first‑line treatment for uncomplicated Plasmodium falciparum malaria in most endemic regions? *

What is the primary mechanism of action of chloroquine against malaria parasites? *