Adrenergic receptors ✓ Passing Score: 50% 📝 Questions: 10 🎓 Practice Quiz Welcome! This is a practice quiz to test your knowledge. Please enter your details below to participate. Your results will be emailed to you upon completion. Your Information Name * Email * Start Quiz → Question 1 of 10 1 Which of the following second messenger pathways is characteristic of $\\\\beta$ adrenergic receptors ($\\\\beta_1$, $\\\\beta_2$, $\\\\beta_3$)? * $\\\\text{Gs} \\\\rightarrow \\\\text{Activation of Adenylyl Cyclase} \\\\rightarrow \\\\text{cAMP}$ $\\\\text{Activation of $\\\\text{MAPK}$ pathway directly}$ $\\\\text{Gq} \\\\rightarrow \\\\text{PLC} \\\\rightarrow \\\\text{IP}_3/\\\\text{DAG}$ $\\\\text{Ion Channel Gating}$ $\\\\text{Gi} \\\\rightarrow \\\\text{Inhibition of Adenylyl Cyclase}$ 2 Stimulation of which adrenergic receptor subtype is most closely associated with the inhibition of adenylyl cyclase, resulting in decreased cyclic AMP ($\\\\text{cAMP}$) levels? * $\\\\alpha_2$ $\\\\text{D}_1$ $\\\\beta_1$ $\\\\alpha_1$ $\\\\beta_3$ 3 A drug that acts as a selective antagonist at $\\\\alpha_1$ receptors would most likely cause which immediate effect? * Bronchoconstriction Increased aqueous humor production Decreased peripheral vascular resistance (leading to hypotension) Decreased renin release from the kidney Bradycardia 4 Which class of adrenergic receptors is primarily coupled to the Gq protein, leading to increased intracellular $\\\\text{IP}_3$ and $\\\\text{DAG}$? * $\\\\alpha_1$ $\\\\alpha_2$ $\\\\text{M}_2$ $\\\\beta_1$ $\\\\beta_2$ 5 Which receptor subtype is primarily responsible for increasing heart rate (positive chronotropy) and contractility (positive inotropy)? * $\\\\alpha_2$ $\\\\text{M}_1$ $\\\\alpha_1$ $\\\\beta_2$ $\\\\beta_1$ 6 In the context of adrenergic receptor classification, what is the primary difference between $\\\\alpha$ and $\\\\beta$ receptors regarding their coupling mechanism? * $\\\\alpha$ receptors use $\\\\text{cAMP}$ exclusively; $\\\\beta$ receptors use $\\\\text{Ca}^{2+}$. $\\\\alpha$ receptors are always inhibitory; $\\\\beta$ receptors are always stimulatory. $\\\\alpha$ receptors primarily utilize $\\\\text{Gq}$ ($\\\\alpha_1$) or $\\\\text{Gi}$ ($\\\\alpha_2$); $\\\\beta$ receptors primarily utilize $\\\\text{Gs}$. $\\\\alpha$ receptors respond only to norepinephrine; $\\\\beta$ receptors respond only to epinephrine. $\\\\alpha$ receptors affect smooth muscle; $\\\\beta$ receptors affect cardiac muscle. 7 Activation of $\\\\alpha_1$ receptors in vascular smooth muscle typically results in which physiological effect? * Increased lipolysis Decreased heart rate Decreased neurotransmitter release Vasodilation Vasoconstriction 8 Which adrenergic receptor subtype is primarily involved in mediating lipolysis in adipose tissue? * $\\\\beta_3$ $\\\\beta_2$ $\\\\alpha_2$ $\\\\beta_1$ $\\\\alpha_1$ 9 Which adrenergic receptor subtype is selectively stimulated by low concentrations of epinephrine and is often located pre-synaptically to inhibit further neurotransmitter release? * $\\\\alpha_{\\\\text{smooth}}$ $\\\\beta_1$ $\\\\alpha_2$ $\\\\alpha_1$ $\\\\beta_2$ 10 Which adrenergic receptor subtype is predominantly found in the smooth muscle of the bronchioles and mediates bronchodilation upon activation? * $\\\\beta_2$ $\\\\alpha_1$ $\\\\beta_1$ $\\\\alpha_2$ $\\\\text{M}_3$ ← Previous Next → Submit Quiz ✓