Introduction/Overview Ivermectin represents a landmark therapeutic agent in the field of antiparasitic chemotherapy. Its discovery, originating from the soil bacterium Streptomyces avermitilis, has had a profound impact on global public…

Introduction/Overview Ivermectin represents a landmark therapeutic agent in the field of antiparasitic chemotherapy. Its discovery, originating from the soil bacterium Streptomyces avermitilis, has had a profound impact on global public…

Introduction/Overview Mebendazole represents a cornerstone agent within the benzimidazole class of anthelmintic drugs, playing a critical role in global public health initiatives against soil-transmitted helminthiases. First introduced in the early…

Introduction/Overview Quinine, a naturally occurring alkaloid derived from the bark of the Cinchona tree, represents one of the oldest and most historically significant therapeutic agents in medicine. Its use for…

1. Introduction/Overview Quinine, a naturally occurring alkaloid extracted from the bark of the Cinchona tree, represents one of the oldest and most historically significant therapeutic agents in medicine. Its use…

Introduction/Overview Primaquine phosphate is an 8-aminoquinoline antimalarial agent of significant historical and contemporary clinical importance. First synthesized in the 1940s, it remains the only drug widely available for the radical…

Introduction/Overview Primaquine phosphate is an 8-aminoquinoline compound that occupies a unique and critical position in the antimalarial pharmacopeia. Unlike most antimalarial agents which target the asexual blood stages of Plasmodium…

Introduction/Overview Ritonavir is a synthetic peptidomimetic agent initially developed as an antiretroviral drug for the management of human immunodeficiency virus (HIV) infection. Its primary clinical significance has evolved from its…

Introduction/Overview Ritonavir is a synthetic peptidomimetic agent initially developed as an antiretroviral drug. Its primary clinical significance has evolved from its direct antiviral activity to its pivotal role as a…

Introduction/Overview Efavirenz represents a cornerstone non-nucleoside reverse transcriptase inhibitor (NNRTI) in the historical and contemporary management of human immunodeficiency virus type 1 (HIV-1) infection. Its development marked a significant advancement…