Antiarrhythmic drugs: Flecainide (Class 1C)
Introduction Flecainide is an antiarrhythmic agent classified under subgroup 1C. It is a potent blocker of sodium and potassium channels with slow unblocking kinetics. While it is effective in treating…
Antiarrhythmic drugs: Mexiletine (Class 1B)
Introduction Mexiletine is an orally active antiarrhythmic agent, classified in subgroup 1B, similar to lidocaine. It is predominantly used for treating ventricular arrhythmias and has proven effective in alleviating chronic…
Antiarrhythmic drugs: Lidocaine (Class 1B)
Introduction Lidocaine is a multifaceted medication primarily known as a local anesthetic, but it also has significant roles as an antiarrhythmic and analgesic agent. Classified as a Class Ib antiarrhythmic…
Antiarrhythmic drugs: Disopyramide (Class 1A)
Introduction Disopyramide is a Class 1a antiarrhythmic agent, primarily used in the treatment of ventricular tachycardia. It functions as a sodium channel blocker, inhibiting conduction by depressing the increase in…
Antiarrhythmic drugs: Quinidine (Class 1A)
Introduction Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. It is a diastereomer of the antimalarial agent quinine, originally derived from the bark of the…
Antiarrhythmic drugs: Procainamide (Class 1A)
Introduction Procainamide is a medication primarily used in the treatment of cardiac arrhythmias, which are irregular heart rhythms. It belongs to the class of antiarrhythmic agents known as Group I…
Classification of Adrenergic Receptors: A Quick Overview
Introduction Adrenergic receptors play a pivotal role in regulating physiological processes and are the target of numerous pharmacological interventions. These receptors are broadly classified into α and β types, with…
Adverse Drug Reactions: On-target and Off-target aspect
Introduction Adverse drug reactions (ADRs) remain a formidable challenge in clinical pharmacology and patient care. They can significantly diminish quality of life, induce severe morbidity and mortality, extend hospital stays,…
The History of Pharmacology
The Intersection of Religion and Medicine At the dawn of human civilization, religion and medicine were inextricably linked. Priests, shamans, and holy people were the original pharmacologists, wielding the power…
Pharmacokinetic Principles: A Comprehensive Guide
Introduction Pharmacokinetics is the science that describes how drugs move within the body and is crucial for rational dosing in clinical settings. This article aims to provide a comprehensive understanding…
