Atropine
Atropine
Generic Name
Atropine
Drug Class
Muscarinic antagonist (anticholinergic)
Mechanism
Competitive blockade of all muscarinic acetylcholine receptors (M1–M5). Increases heart rate, reduces secretions, dilates pupil, relaxes smooth muscle.
Contraindications
- Glaucoma with narrow angle (risk of acute angle‑closure)
- Mechanical ileus
- Severe peripheral vascular disease (risk of ischemia)
- History of pro‑arrhythmic QT‑prolongation (at high doses)
Clinical Pearls
- Pediatrics: 0.01–0.02 mg/kg IM/IV for bradycardia; 0.1 mg/kg eye drops for mydriasis.
- Pregnancy: Category C. Use only if benefits > dangers.
- Breastfeeding: Low transfer; minimal but avoid if mother is of child‑bearing potential.
Clinical Notes
| Drug Name | Atropine |
|---|---|
| Generic Name | Atropine sulfate |
| Drug Class | Anticholinergic/Antimuscarinic |
| Indications/Uses | Bradycardia, organophosphate poisoning, mydriasis |
| Common Side Effects | Dry mouth, tachycardia, urinary retention, blurred vision |
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare providers and official prescribing information for medical decisions.
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