Myocardial infarction

Understanding Alteplase: The Tissue Plasminogen Activator You Need to Know

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alteplase a tissue plasminogen activator

Introduction Alteplaseย (also referred to as recombinant tissue plasminogen activator or rt-PA) is a cornerstone of thrombolytic therapy, widely used to treat acute ischemic stroke, acute myocardial infarction, and other thromboembolic conditions. As a bioengineered form of tissue plasminogen activator (tPA),ย alteplaseย exerts its therapeutic effect by converting plasminogen to plasmin, thereby dissolving clots that obstruct blood flow … Read more

Angina Pectoris: A Comprehensive Guide

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angina featured image

Angina pectoris, commonly known as angina, is a type of chest pain caused by reduced blood flow to the heart. This article provides a detailed exploration of angina pectoris, including its classification, types, pathophysiology, and treatment for individual types. We’ll also incorporate flowcharts to help illustrate these concepts. What is Angina Pectoris? Angina pectoris is … Read more

Ischemic Heart Disease: Causes, signs and treatment options

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Ischemic Heart disease

1. Definition & Epidemiology Ischemic heart disease (IHD)โ€”also called coronary artery disease (CAD)โ€”is defined by impaired blood supply (ischemia) to the myocardium, usually due to narrowing or obstruction of the coronary arteries by atherosclerotic plaque. IHD is the leading cause of morbidity and mortality worldwide, particularly affecting adults over age 40 and those with major cardiovascular … Read more

How Ischemic Heart Disease is treated?

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Pharmacology Mentor

The treatment of ischemic heart disease aims to improve blood flow to the heart muscle.ย This can be achieved through a combination of lifestyle changes, medications, and in some cases, surgical procedures. Drug Class Examples Pharmacokinetics Mechanism of Action/Pharmacological Actions Therapeutic Uses Adverse Effects Contraindications Drug Interactions Antiplatelet Drugs Aspirin, Clopidogrel Rapidly absorbed in the stomach … Read more

Sympatholytics/Adrenergic antagonists

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adrenergic antagonists or sympatholytics

Introduction Have you ever wondered about the drugs that counteract the effects of the sympathetic nervous system? Sympatholytics, also known as adrenergic antagonists, are one such class of drugs. This article will dive into the classification, pharmacological actions, clinical uses, adverse effects, and contraindications of different types of sympatholytic drugs. So, let’s get started! Sympatholytics … Read more