Hypertension

Pharmacology of Alpha-Blockers

by
alpha-blockers

Introduction Alpha-adrenergic receptor antagonists, commonly referred to asย alpha-blockers, form a crucial element in the pharmacologic management of several cardiovascular and genitourinary conditions. Byย blocking alpha-1 and/or alpha-2 adrenergic receptors, these agents cause a diverse array of effects, fromย vasodilationย in peripheral blood vessels toย smooth muscle relaxationย in the bladder neck and prostate. Clinicians frequently use alpha-blockers to treatย hypertension,ย benign prostatic … Read more

Pharmacology of Beta-Blockers

by
beta-blockers

Introduction Beta blockers, also known as ฮฒ-adrenergic receptor antagonists, are a foundational class of cardiovascular drugs used to treat hypertension, ischemic heart disease, heart failure, arrhythmias, and other conditions. By blocking the actions of catecholaminesโ€”particularly norepinephrine (noradrenaline) and epinephrine (adrenaline)โ€”at ฮฒ-adrenergic receptors, these agents reduce sympathetic overstimulation and exert a range of beneficial clinical effects. … Read more

Pharmacology of Alpha Agonists

by
alpha blockers

Introduction to Alpha Agonists: Alpha agonists are a class of drugs that primarily act on alpha-adrenergic receptors. These receptors are part of the sympathetic nervous system and respond to the neurotransmitters epinephrine (adrenaline) and norepinephrine (noradrenaline). When activated, alpha receptors typically cause constriction of blood vessels and an increase in blood pressure. Alpha agonists can … Read more

Obesity: What We Know and What We Can Do?

by
Obesity

Introduction and scope Obesity is a chronic, relapsing, multifactorial disease marked by excess adiposity that impairs health. It now affects more than one billion people worldwide, including over 650 million adults, with prevalence rising in nearly every region and across all socioeconomic strata. Obesity substantially increases risks of type 2 diabetes, cardiovascular disease, certain cancers, … Read more

Sympatholytics/Adrenergic antagonists

by
adrenergic antagonists or sympatholytics

Introduction Have you ever wondered about the drugs that counteract the effects of the sympathetic nervous system? Sympatholytics, also known as adrenergic antagonists, are one such class of drugs. This article will dive into the classification, pharmacological actions, clinical uses, adverse effects, and contraindications of different types of sympatholytic drugs. So, let’s get started! Sympatholytics … Read more