Pharmacology of Cephalosporin antibiotics
Cephalosporin antibiotics are beta-lactam antibiotics derived from Cephalosporium acremonium, classified by generations based on their antimicrobial spectra and pharmacokinetic properties. They are among the most utilized antibiotics globally, due to broad efficacy and good safety profile. I. Mechanism of Action Cephalosporins bind to bacterial penicillin-binding proteins (PBPs) and inhibit the final transpeptidation step of peptidoglycan synthesis in … Read more