Antiplatelet

Pharmacology of Antiplatelet Drugs

by
antiplatelet drugs

Antiplatelet drugs inhibit platelet activation and aggregation, thereby reducing the risk of arterial thrombus formation—a critical strategy in preventing and managing cardiovascular diseases like myocardial infarction, stroke, and peripheral arterial disease. Classification & Mechanisms of Action Class & Examples Mechanism Key Indications COX-1 InhibitorsAspirin Irreversibly inhibits cyclooxygenase-1 (COX-1), blocking thromboxane A2 (TXA2) synthesis and platelet … Read more

Aspirin: A Comprehensive Pharmacological Overview

by
Aspirin

Aspirin, scientifically known as acetylsalicylic acid (ASA), is a cornerstone in the world of nonsteroidal anti-inflammatory drugs (NSAIDs). With its multifaceted roles as an analgesic, antipyretic, and anti-inflammatory agent, aspirin has secured its position as one of the most frequently administered medications worldwide. Mechanism of Action At the heart of aspirin’s mechanism is its ability to irreversibly … Read more

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

by
NSAIDs

Non-steroidal anti-inflammatory drugs (NSAIDs) are cornerstone analgesic, antipyretic, and anti-inflammatory agents whose primary mechanism is inhibition of cyclooxygenase (COX) enzymes to reduce prostaglandin and thromboxane synthesis. A complete pharmacology chapter should cover COX biology, detailed classification, pharmacokinetics/dynamics, therapeutic uses, adverse effects, drug interactions, special populations, and evidence-based risk mitigation strategies from standard pharmacology texts and … Read more