Pharmacology of Beta-Blockers

beta-blockers

Introduction Beta blockers, also known as β-adrenergic receptor antagonists, are a foundational class of cardiovascular drugs used to treat hypertension, ischemic heart disease, heart failure, arrhythmias, and other conditions. By blocking the actions of catecholamines—particularly norepinephrine (noradrenaline) and epinephrine (adrenaline)—at β-adrenergic receptors, these agents reduce sympathetic overstimulation and exert a range of beneficial clinical effects. … Read more

Treatment of Angina Pectoris: A Comprehensive Guide

angina pectoris

Pharmacologic treatment of angina pectoris relies on antianginal agents that improve the myocardial oxygen supply–demand balance for symptom control and on adjunctive therapies tailored to mechanism (obstructive, vasospastic, microvascular), heart rate, blood pressure, and comorbidities under contemporary chronic coronary syndrome guidelines. Core antianginal classes include nitrates, beta-blockers, calcium channel blockers, late sodium current inhibition (ranolazine), … Read more