Table of ContentsCHEMICAL STRUCTURE AND CLASSIFICATION The Macrolide Ring Commonly Used Macrolides Macrolide Generations Mechanism of ActionInhibition of Bacterial Protein Synthesis Bacteriostatic vs. Bactericidal Additional Anti-inflammatory Effects SPECTRUM OF ANTIBACTERIAL ACTIVITY Gram-Positive Organisms Atypical Pathogens Gram-Negative Organisms Other Notable Bacteria PharmacokineticsAbsorptionDistribution Metabolism Excretion Half-Life and Dosing Clinical UsesRespiratory Tract Infections Skin and Soft Tissue Infections … Continue reading Pharmacology of Macrolides