Table of ContentsIntroduction: The Gatekeepers of Drug DevelopmentWhat Are Preclinical Trials?Phase 1: In Vitro Studies (The “Test Tube” Phase)High-Throughput Screening (HTS)Key In Vitro AssaysPhase 2: Safety Pharmacology (The “Vital Systems”)Phase 3: Toxicology Studies (Defining the Limits)Types of Toxicology StudiesCalculating the Human Dose: The NOAELAnimal Models in ResearchWhy Animals?Common ModelsEthical Considerations: The 3RsThe Pros and Cons … Continue reading Preclinical Trials: Things You Need to Know