Structure-Activity Relationship (SAR)

Table of ContentsIntroductionStructure-Activity Relationship (SAR)DefinitionImportanceKey Concepts in SARQuantitative Structure-Activity Relationship (QSAR)Ligand-Based Drug Design (LBDD)3D Pharmacophore ModelingMolecular DescriptorsPhysicochemical PropertiesTopological IndicesSAR Methods and TechniquesFragment-Based ApproachComparative Molecular Field Analysis (CoMFA)Comparative Molecular Similarity Indices Analysis (CoMSIA)SAR Studies in Drug DesignLead OptimizationTarget IdentificationLimitations of SARThe Future of SAR in Drug DiscoveryConclusionIntroduction Structure-Activity Relationship (SAR) are an important aspect of chemistry … Continue reading Structure-Activity Relationship (SAR)