Table of ContentsIntroductionDiscovery and Evolution of SSRIsMechanism of ActionSerotonin Reuptake InhibitionDownstream Neurochemical AdaptationsCommonly Prescribed SSRIsFluoxetineSertralineParoxetineFluvoxamineCitalopram and EscitalopramPharmacokineticsAbsorption and DistributionMetabolismEliminationClinical IndicationsDose, Administration, and Treatment DurationInitiation and TitrationTime to Therapeutic ResponseMaintenance and Relapse PreventionAdverse EffectsGastrointestinal UpsetSexual DysfunctionWeight ChangesCentral Nervous System EffectsSuicidality Risk in Younger PatientsSerotonin SyndromeBleeding DiathesisHyponatremia / SIADHDrug InteractionsDiscontinuation SyndromeOverdose and ToxicitySpecial PopulationsPediatric PatientsGeriatric PatientsPregnancy and … Continue reading Pharmacology of Selective serotonin reuptake inhibitors (SSRIs)