Table of ContentsIntroductionHistorical Perspective and DevelopmentMechanism of ActionOverviewDetailed Binding SitesBacteriostatic vs. Bactericidal PotentialAntimicrobial SpectrumGram-Positive BacteriaGram-Negative Aerobes and AnaerobesAtypical PathogensPharmacokineticsFormulation and Route of AdministrationDistributionMetabolismExcretionHalf-LifeClinical IndicationsVancomycin-Resistant Enterococcus faecium (VREF) InfectionsComplicated Skin and Skin Structure InfectionsBacteremia Due to Multi-Resistant StaphylococciRespiratory Tract Infections (Off-Label)Use in Special PopulationsDosage and AdministrationStandard Adult DoseInfusion ConsiderationsDuration of TherapyAdjustments in Hepatic DysfunctionAdverse EffectsLocal Infusion-Related … Continue reading Pharmacology of Quinupristin-dalfopristin