Pharmacology of Antiplatelet Drugs

Table of ContentsIntroductionPlatelet Biology and the Basis for Antiplatelet TherapyPlatelet Activation and AggregationRationale for Antiplatelet DrugsClassification of Antiplatelet Drugs1. Cyclooxygenase-1 (COX-1) Inhibitors2. P2Y₁₂ (ADP) Receptor Inhibitors3. Glycoprotein IIb/IIIa (GPIIb/IIIa) Inhibitors4. Phosphodiesterase Inhibitors and Adjuvants5. Protease-Activated Receptor-1 (PAR-1) AntagonistsCyclooxygenase-1 (COX-1) InhibitorsAspirin (Acetylsalicylic Acid)Mechanism of ActionPharmacokineticsClinical UsesAdverse Effects and PrecautionsP2Y₁₂ (ADP) Receptor InhibitorsOverviewClopidogrelPrasugrelTicagrelorCangrelorTiclopidineGlycoprotein IIb/IIIa (GPIIb/IIIa) InhibitorsKey AgentsMechanism … Continue reading Pharmacology of Antiplatelet Drugs