Table of ContentsIntroductionChemical and Historical OverviewChemical Structure and DerivationHistorical SignificanceClassificationMechanisms of ActionGABA-A Receptor ModulationAdditional Sites of ActionResultant CNS DepressionPharmacokineticsAbsorption and DistributionMetabolismSpecial ConsiderationsTherapeutic UsesSedation and HypnosisAnticonvulsant TherapyInduction of AnesthesiaMedically Induced ComaMiscellaneousAdverse EffectsCNS DepressionTolerance and DependenceParadoxical ExcitementHepatic Enzyme InductionAllergic ReactionsToxicity and OverdosePresentation of OverdoseManagementPrognosisWithdrawal and DependenceWithdrawal SyndromeManagement of WithdrawalAbuse and MisuseDrug InteractionsSynergistic CNS DepressionEnzyme Induction EffectsPorphyriaComparisons to … Continue reading Pharmacology of Barbiturates