Table of ContentsIntroductionPhysiology of Alpha-Adrenergic ReceptorsClassification of Alpha-BlockersNonselective Alpha-BlockersSelective Alpha-1 BlockersSelective Alpha-2 BlockersPharmacokinetics of Alpha-BlockersAbsorption and BioavailabilityDistributionMetabolismElimination and Half-LifePharmacodynamics and Mechanisms of ActionVascular EffectsGenitourinary EffectsCardiac and Other EffectsClinical IndicationsHypertensionBenign Prostatic Hyperplasia (BPH)PheochromocytomaOther UsesAdverse EffectsPostural (Orthostatic) HypotensionReflex Tachycardia and PalpitationsHeadache, Dizziness, FatigueNasal CongestionAbnormal EjaculationOthersDrug InteractionsAntihypertensivesPDE5 InhibitorsCYP450 InhibitorsCaution with Beta-BlockersComparisons with Beta-Blockers and Other AntihypertensivesSpecific Alpha-Blocking AgentsPrazosinTerazosinDoxazosinTamsulosinSilodosinPhentolaminePhenoxybenzamineClinical … Continue reading Pharmacology of Alpha-Blockers